Ketamine Infusions for Chronic Daily Headaches

Ketamine is an anesthetic drug that has been shown to improve pain control after surgery and for chronic pain conditions. The KetHead Study is a multi-centre randomized controlled trial of efficacy and safety of intravenous ketamine for chronic daily headaches. The study aims to look at the pain-relieving effect and optimal dose of ketamine infusions for CDH, as well as its effect on sleep, functional activity and overall quality of life.

You may qualify if you:

  • Are aged 18 – 75 years
  • Have headaches for at least 4 hours per day for at least 15 days per month

Participation involves:

  • Completing a headache diary 1 month before and 3 months after the infusion
  • Being able to receive a 1 day infusion at Toronto Western Hospital
  • Wearing an actigraph watch to measure your sleep and physical activity
  • Compensation to cover travel and parking costs ($30 CAD)

For more information about this study and to find out if you’re eligible, please reach out to the study coordinator: didem.bozak@wchospital.ca.