Prospective Saddle block for Penile Inversion Vaginoplasty Study

Researchers at Women’s College Hospital are focused on improving pain control for patients undergoing penile inversion vaginoplasty, a gender-affirming surgery. This study is testing whether adding a low-dose spinal (intrathecal) injection of morphine to standard pain management before surgery can reduce the need for opioids and improve recovery in the first 24 hours after surgery.

You may qualify if you:

  • Are aged 18 – 70 years
  • Are undergoing penile inversion vaginoplasty
  • Are classified as ASA physical status I–III

Participation involves:

  • Receiving either a saddle block with intrathecal morphine or a placebo injection before surgery
  • Completing assessments of pain, recovery quality, and satisfaction within 48 hours post-surgery
  • Monitoring for side effects and complications related to the block or opioids

For more information about this study and to find out if you’re eligible, please reach out to the study coordinator: didem.bozak@wchospital.ca